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Genome-wide analysis of genetic and epigenetic control of programmed DNA deletion

During the development of the somatic genome from the Paramecium germline genome the bulk of the copies of ∼45 000 unique, internal eliminated sequences (IESs) are deleted. IES targeting is facilitated by two small RNA (sRNA) classes: scnRNAs, which relay epigenetic information from the parental nuc...

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Detalles Bibliográficos
Autores principales: Swart, Estienne C., Wilkes, Cyril Denby, Sandoval, Pamela Y., Arambasic, Miroslav, Sperling, Linda, Nowacki, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132734/
https://www.ncbi.nlm.nih.gov/pubmed/25016527
http://dx.doi.org/10.1093/nar/gku619