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Microscopic mechanism of DNA damage searching by hOGG1

The DNA backbone is often considered a track that allows long-range sliding of DNA repair enzymes in their search for rare damage sites in DNA. A proposed exemplar of DNA sliding is human 8-oxoguanine ((o)G) DNA glycosylase 1 (hOGG1), which repairs mutagenic (o)G lesions in DNA. Here we use our high...

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Detalles Bibliográficos
Autores principales:	Rowland, Meng M., Schonhoft, Joseph D., McKibbin, Paige L., David, Sheila S., Stivers, James T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132736/ https://www.ncbi.nlm.nih.gov/pubmed/25016526 http://dx.doi.org/10.1093/nar/gku621

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