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Structural determinants of an internal ribosome entry site that direct translational reading frame selection

The dicistrovirus intergenic internal ribosome entry site (IGR IRES) directly recruits the ribosome and initiates translation using a non-AUG codon. A subset of IGR IRESs initiates translation in either of two overlapping open reading frames (ORFs), resulting in expression of the 0 frame viral struc...

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Detalles Bibliográficos
Autores principales: Ren, Qian, Au, Hilda H.T., Wang, Qing S., Lee, Seonghoon, Jan, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132737/
https://www.ncbi.nlm.nih.gov/pubmed/25038250
http://dx.doi.org/10.1093/nar/gku622