Road rules for traffic on DNA—systematic analysis of transcriptional roadblocking in vivo

Genomic DNA is bound by many proteins that could potentially impede elongation of RNA polymerase (RNAP), but the factors determining the magnitude of transcriptional roadblocking in vivo are poorly understood. Through systematic experiments and modeling, we analyse how roadblocking by the lac repres...

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Detalles Bibliográficos
Autores principales: Hao, Nan, Krishna, Sandeep, Ahlgren-Berg, Alexandra, Cutts, Erin E., Shearwin, Keith E., Dodd, Ian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132739/
https://www.ncbi.nlm.nih.gov/pubmed/25034688
http://dx.doi.org/10.1093/nar/gku627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132739/
https://www.ncbi.nlm.nih.gov/pubmed/25034688
http://dx.doi.org/10.1093/nar/gku627

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