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Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins

Trithorax and polycomb group proteins are generally thought to antagonize one another. The trithorax family member MLL (myeloid/lymphoid or mixed-lineage leukemia) is presumed to activate Hox expression, counteracting polycomb-mediated repression. PC4 and SF2 interacting protein 1 (PSIP1)/p75, also...

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Detalles Bibliográficos
Autores principales:	Pradeepa, Madapura M., Grimes, Graeme R., Taylor, Gillian C.A., Sutherland, Heidi G., Bickmore, Wendy A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132756/ https://www.ncbi.nlm.nih.gov/pubmed/25056311 http://dx.doi.org/10.1093/nar/gku647

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