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Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer

BACKGROUND: Transforming growth factor (TGF)-β plays a pivotal role in cancer progression through regulating cancer cell proliferation, invasion, and remodeling of the tumor microenvironment. Cancer-associated fibroblasts (CAFs) are the predominant type of stromal cell, in which TGF-β signaling is a...

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Detalles Bibliográficos
Autores principales:	Horie, Masafumi, Saito, Akira, Noguchi, Satoshi, Yamaguchi, Yoko, Ohshima, Mitsuhiro, Morishita, Yasuyuki, Suzuki, Hiroshi I, Kohyama, Tadashi, Nagase, Takahide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132906/ https://www.ncbi.nlm.nih.gov/pubmed/25107280 http://dx.doi.org/10.1186/1471-2407-14-580

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