Cargando…

Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer

BACKGROUND: Transforming growth factor (TGF)-β plays a pivotal role in cancer progression through regulating cancer cell proliferation, invasion, and remodeling of the tumor microenvironment. Cancer-associated fibroblasts (CAFs) are the predominant type of stromal cell, in which TGF-β signaling is a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Horie, Masafumi, Saito, Akira, Noguchi, Satoshi, Yamaguchi, Yoko, Ohshima, Mitsuhiro, Morishita, Yasuyuki, Suzuki, Hiroshi I, Kohyama, Tadashi, Nagase, Takahide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132906/ https://www.ncbi.nlm.nih.gov/pubmed/25107280 http://dx.doi.org/10.1186/1471-2407-14-580

Ejemplares similares

An Integrated Expression Profiling Reveals Target Genes of TGF-β and TNF-α Possibly Mediated by MicroRNAs in Lung Cancer Cells
por: Saito, Akira, et al.
Publicado: (2013)

Correction: An Integrated Expression Profiling Reveals Target Genes of TGF-β and TNF-α Possibly Mediated by MicroRNAs in Lung Cancer Cells
por: Saito, Akira, et al.
Publicado: (2014)

TGF-β Signaling in Lung Health and Disease
por: Saito, Akira, et al.
Publicado: (2018)

YAP and TAZ modulate cell phenotype in a subset of small cell lung cancer
por: Horie, Masafumi, et al.
Publicado: (2016)

The Role of TGF-β Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis
por: Saito, Akira, et al.
Publicado: (2018)

Targeting hepatocyte growth factor in epithelial–stromal interactions in an in vitro experimental model of human periodontitis
por: Yamaguchi, Yoko, et al.
Publicado: (2021)

Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells
por: Matsuzaki, Hirotaka, et al.
Publicado: (2015)

Lymphotoxin β Receptor Signaling Induces IL-8 Production in Human Bronchial Epithelial Cells
por: Mikami, Yu, et al.
Publicado: (2014)

YAP/TAZ Signaling as a Molecular Link between Fibrosis and Cancer
por: Noguchi, Satoshi, et al.
Publicado: (2018)

Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis
por: Horie, Masafumi, et al.
Publicado: (2016)

TGF-β-mediated epithelial–mesenchymal transition and tumor-promoting effects in CMT64 cells are reflected in the transcriptomic signature of human lung adenocarcinoma
por: Miyashita, Naoya, et al.
Publicado: (2021)

Dynamic change in respiratory resistance during inspiratory and expiratory phases of tidal breathing in patients with chronic obstructive pulmonary disease
por: Yamauchi, Yasuhiro, et al.
Publicado: (2012)

The incidence and risk factors of asymptomatic primary spontaneous pneumothorax detected during health check-ups
por: Mitani, Akihisa, et al.
Publicado: (2017)

MicroRNA profiling in gingival crevicular fluid of periodontitis—a pilot study
por: Saito, Akira, et al.
Publicado: (2017)

TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts
por: Noguchi, Satoshi, et al.
Publicado: (2017)

Regulation of TGF-β-mediated endothelial-mesenchymal transition by microRNA-27
por: Suzuki, Hiroshi I., et al.
Publicado: (2017)

Pleural thickening on screening chest X-rays: a single institutional study
por: Saito, Akira, et al.
Publicado: (2019)

ASCL1 regulates super‐enhancer‐associated miRNAs to define molecular subtypes of small cell lung cancer
por: Miyakawa, Kazuko, et al.
Publicado: (2022)

Serum Reactive Oxygen Metabolite Levels Predict Severe Exacerbations of Asthma
por: Nakamoto, Keitaro, et al.
Publicado: (2016)

Differential effects of a common splice site polymorphism on the generation of OAS1 variants in human bronchial epithelial cells
por: Noguchi, Satoshi, et al.
Publicado: (2013)

Targeting TGF-β Signaling by Antisense Oligonucleotide-mediated Knockdown of TGF-β Type I Receptor
por: Kemaladewi, Dwi U, et al.
Publicado: (2014)

Stromal Modulators of TGF-β in Cancer
por: Costanza, Brunella, et al.
Publicado: (2017)

Knockdown of RhoQ, a member of Rho GTPase, accelerates TGF-β-induced EMT in human lung adenocarcinoma
por: Satoh, Kotone, et al.
Publicado: (2022)

MxA transcripts with distinct first exons and modulation of gene expression levels by single-nucleotide polymorphisms in human bronchial epithelial cells
por: Noguchi, Satoshi, et al.
Publicado: (2012)

TUFM-knockdown inhibits the migration and proliferation of gastrointestinal stromal tumor cells
por: Weng, Xiaoyuan, et al.
Publicado: (2020)

Current clinical management of gastrointestinal stromal tumor
por: Akahoshi, Kazuya, et al.
Publicado: (2018)

Pulmonary carcinoid tumour with remarkably high levels of pro-gastrin-releasing peptide: A case report
por: Nakagawa, Natsuki, et al.
Publicado: (2023)

A case of Meigs’ syndrome with preceding pericardial effusion in advance of pleural effusion
por: Okuda, Kenichi, et al.
Publicado: (2016)

Stromal and epithelial TGF-β signaling in mammary tumorigenesis
por: Moses, HL, et al.
Publicado: (2005)

Persistent second cervical intersegmental artery diagnosed by MR angiography
por: Uchino, Akira, et al.
Publicado: (2019)

Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-β-associated fibroblast activation in murine pulmonary fibrosis
por: Souma, Kunihiko, et al.
Publicado: (2018)

Designer TGFβ Superfamily Ligands with Diversified Functionality
por: Allendorph, George P., et al.
Publicado: (2011)

Low-Grade Endometrial Stromal Sarcoma with a Nodule-in-Nodule Appearance in Preoperative Magnetic Resonance Images
por: Nakamura, Mitsuhiro, et al.
Publicado: (2020)

Corrigendum to “Low-Grade Endometrial Stromal Sarcoma with a Nodule-in-Nodule Appearance in Preoperative Magnetic Resonance Images”
por: Nakamura, Mitsuhiro, et al.
Publicado: (2021)

Recovery with a regular dose of antibiotics from bacillary hemoglobinuria in a Holstein cow
por: TAKAGI, Mitsuhiro, et al.
Publicado: (2016)

Knockdown of stromal interaction molecule 1 inhibits proliferation of colorectal cancer cells by inducing apoptosis
por: Yang, Dong, et al.
Publicado: (2018)

Signal Processing in the TGF-β Superfamily Ligand-Receptor Network
por: Vilar, Jose M. G, et al.
Publicado: (2006)

Stromal TGF-β signaling induces AR activation in prostate cancer
por: Yang, Feng, et al.
Publicado: (2014)

Relationships among Smoking Habits, Airflow Limitations, and Metabolic Abnormalities in School Workers
por: Horie, Masafumi, et al.
Publicado: (2013)

Targeting TGFβR2‐mutant tumors exposes vulnerabilities to stromal TGFβ blockade in pancreatic cancer
por: Huang, Huocong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_3kkkjlg7n6ll66e9gufm538l9j