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Frequency-modulated light scattering interferometry employed for optical properties and dynamics studies of turbid media
In the present work, fiber-based frequency-modulated light scattering interferometry (FMLSI) is developed and employed for studies of optical properties and dynamics in liquid phantoms made from Intralipid(®). The fiber-based FMLSI system retrieves the optical properties by examining the intensity f...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Optical Society of America
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133008/ https://www.ncbi.nlm.nih.gov/pubmed/25136504 http://dx.doi.org/10.1364/BOE.5.002810 |
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author | Mei, Liang Somesfalean, Gabriel Svanberg, Sune |
author_facet | Mei, Liang Somesfalean, Gabriel Svanberg, Sune |
author_sort | Mei, Liang |
collection | PubMed |
description | In the present work, fiber-based frequency-modulated light scattering interferometry (FMLSI) is developed and employed for studies of optical properties and dynamics in liquid phantoms made from Intralipid(®). The fiber-based FMLSI system retrieves the optical properties by examining the intensity fluctuations through the turbid medium in a heterodyne detection scheme using a continuous-wave frequency-modulated coherent light source. A time resolution of 21 ps is obtained, and the experimental results for the diluted Intralipid phantoms show good agreement with the predicted results based on published data. The present system shows great potential for assessment of optical properties as well as dynamic studies in liquid phantoms, dairy products, and human tissues. |
format | Online Article Text |
id | pubmed-4133008 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Optical Society of America |
record_format | MEDLINE/PubMed |
spelling | pubmed-41330082014-08-18 Frequency-modulated light scattering interferometry employed for optical properties and dynamics studies of turbid media Mei, Liang Somesfalean, Gabriel Svanberg, Sune Biomed Opt Express Article In the present work, fiber-based frequency-modulated light scattering interferometry (FMLSI) is developed and employed for studies of optical properties and dynamics in liquid phantoms made from Intralipid(®). The fiber-based FMLSI system retrieves the optical properties by examining the intensity fluctuations through the turbid medium in a heterodyne detection scheme using a continuous-wave frequency-modulated coherent light source. A time resolution of 21 ps is obtained, and the experimental results for the diluted Intralipid phantoms show good agreement with the predicted results based on published data. The present system shows great potential for assessment of optical properties as well as dynamic studies in liquid phantoms, dairy products, and human tissues. Optical Society of America 2014-07-28 /pmc/articles/PMC4133008/ /pubmed/25136504 http://dx.doi.org/10.1364/BOE.5.002810 Text en © 2014 Optical Society of America author-open |
spellingShingle | Article Mei, Liang Somesfalean, Gabriel Svanberg, Sune Frequency-modulated light scattering interferometry employed for optical properties and dynamics studies of turbid media |
title | Frequency-modulated light scattering interferometry employed for optical properties and dynamics studies of turbid media |
title_full | Frequency-modulated light scattering interferometry employed for optical properties and dynamics studies of turbid media |
title_fullStr | Frequency-modulated light scattering interferometry employed for optical properties and dynamics studies of turbid media |
title_full_unstemmed | Frequency-modulated light scattering interferometry employed for optical properties and dynamics studies of turbid media |
title_short | Frequency-modulated light scattering interferometry employed for optical properties and dynamics studies of turbid media |
title_sort | frequency-modulated light scattering interferometry employed for optical properties and dynamics studies of turbid media |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133008/ https://www.ncbi.nlm.nih.gov/pubmed/25136504 http://dx.doi.org/10.1364/BOE.5.002810 |
work_keys_str_mv | AT meiliang frequencymodulatedlightscatteringinterferometryemployedforopticalpropertiesanddynamicsstudiesofturbidmedia AT somesfaleangabriel frequencymodulatedlightscatteringinterferometryemployedforopticalpropertiesanddynamicsstudiesofturbidmedia AT svanbergsune frequencymodulatedlightscatteringinterferometryemployedforopticalpropertiesanddynamicsstudiesofturbidmedia |