The potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures

The ex vivo and in vivo imaging, and quantitative characterization of the degradation of surgical sutures (∼500 μm diameter) up to ∼1cm depth is demonstrated using a custom dark-field photo-acoustic microscope (PAM). A practical algorithm is developed to accurately measure the suture diameter during...

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Detalles Bibliográficos
Autores principales: Aguirre, Juan, Morales-Dalmau, Jordi, Funk, Lutz, Jara, Francesc, Turon, Pau, Durduran, Turgut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133012/
https://www.ncbi.nlm.nih.gov/pubmed/25136508
http://dx.doi.org/10.1364/BOE.5.002856
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author Aguirre, Juan
Morales-Dalmau, Jordi
Funk, Lutz
Jara, Francesc
Turon, Pau
Durduran, Turgut
author_facet Aguirre, Juan
Morales-Dalmau, Jordi
Funk, Lutz
Jara, Francesc
Turon, Pau
Durduran, Turgut
author_sort Aguirre, Juan
collection PubMed
description The ex vivo and in vivo imaging, and quantitative characterization of the degradation of surgical sutures (∼500 μm diameter) up to ∼1cm depth is demonstrated using a custom dark-field photo-acoustic microscope (PAM). A practical algorithm is developed to accurately measure the suture diameter during the degradation process. The results from tissue simulating phantoms and mice are compared to ex vivo measurements with an optical microscope demonstrating that PAM has a great deal of potential to characterize the degradation process of surgical sutures. The implications of this work for industrial applications are discussed.
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spelling pubmed-41330122014-08-18 The potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures Aguirre, Juan Morales-Dalmau, Jordi Funk, Lutz Jara, Francesc Turon, Pau Durduran, Turgut Biomed Opt Express Article The ex vivo and in vivo imaging, and quantitative characterization of the degradation of surgical sutures (∼500 μm diameter) up to ∼1cm depth is demonstrated using a custom dark-field photo-acoustic microscope (PAM). A practical algorithm is developed to accurately measure the suture diameter during the degradation process. The results from tissue simulating phantoms and mice are compared to ex vivo measurements with an optical microscope demonstrating that PAM has a great deal of potential to characterize the degradation process of surgical sutures. The implications of this work for industrial applications are discussed. Optical Society of America 2014-07-29 /pmc/articles/PMC4133012/ /pubmed/25136508 http://dx.doi.org/10.1364/BOE.5.002856 Text en © 2014 Optical Society of America author-open
spellingShingle Article
Aguirre, Juan
Morales-Dalmau, Jordi
Funk, Lutz
Jara, Francesc
Turon, Pau
Durduran, Turgut
The potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures
title The potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures
title_full The potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures
title_fullStr The potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures
title_full_unstemmed The potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures
title_short The potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures
title_sort potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133012/
https://www.ncbi.nlm.nih.gov/pubmed/25136508
http://dx.doi.org/10.1364/BOE.5.002856
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