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EVA-1 Functions as an UNC-40 Co-receptor to Enhance Attraction to the MADD-4 Guidance Cue in Caenorhabditis elegans

We recently discovered a secreted and diffusible midline cue called MADD-4 (an ADAMTSL) that guides migrations along the dorsoventral axis of the nematode Caenorhabditis elegans. We showed that the transmembrane receptor, UNC-40 (DCC), whose canonical ligand is the UNC-6 (netrin) guidance cue, is re...

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Detalles Bibliográficos
Autores principales:	Chan, Kevin Ka Ming, Seetharaman, Ashwin, Bagg, Rachel, Selman, Guillermo, Zhang, Yuqian, Kim, Joowan, Roy, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133157/ https://www.ncbi.nlm.nih.gov/pubmed/25122090 http://dx.doi.org/10.1371/journal.pgen.1004521

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