Conditional Inactivation of Upstream Binding Factor Reveals Its Epigenetic Functions and the Existence of a Somatic Nucleolar Precursor Body

Upstream Binding Factor (UBF) is a unique multi-HMGB-box protein first identified as a co-factor in RNA polymerase I (RPI/PolI) transcription. However, its poor DNA sequence selectivity and its ability to generate nucleosome-like nucleoprotein complexes suggest a more generalized role in chromatin s...

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Detalles Bibliográficos
Autores principales: Hamdane, Nourdine, Stefanovsky, Victor Y., Tremblay, Michel G., Németh, Attila, Paquet, Eric, Lessard, Frédéric, Sanij, Elaine, Hannan, Ross, Moss, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133168/
https://www.ncbi.nlm.nih.gov/pubmed/25121932
http://dx.doi.org/10.1371/journal.pgen.1004505

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