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A Maladaptive Role for EP4 Receptors in Mouse Mesangial Cells

Roles of the prostaglandin E2 E-prostanoid 4 receptor (EP4) on extracellular matrix (ECM) accumulation induced by TGF-β1 in mouse glomerular mesangial cells (GMCs) remain unknown. Previously, we have identified that TGF-β1 stimulates the expression of FN and Col I in mouse GMCs. Here we asked whethe...

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Detalles Bibliográficos
Autores principales: Yang, Guang-xia, Xu, Yu-yin, Fan, Ya-ping, Wang, Jing, Chen, Xiao-lan, Zhang, Yi-de, Wu, Jian-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133176/
https://www.ncbi.nlm.nih.gov/pubmed/25122504
http://dx.doi.org/10.1371/journal.pone.0104091