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The Relationship between Muscle Fiber Type-Specific PGC-1α Content and Mitochondrial Content Varies between Rodent Models and Humans

PGC-1α regulates critical processes in muscle physiology, including mitochondrial biogenesis, lipid metabolism and angiogenesis. Furthermore, PGC-1α was suggested as an important regulator of fiber type determination. However, whether a muscle fiber type-specific PGC-1α content exists, whether PGC-1...

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Detalles Bibliográficos
Autores principales: Gouspillou, Gilles, Sgarioto, Nicolas, Norris, Brandon, Barbat-Artigas, Sébastien, Aubertin-Leheudre, Mylène, Morais, Jose A., Burelle, Yan, Taivassalo, Tanja, Hepple, Russell T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133187/
https://www.ncbi.nlm.nih.gov/pubmed/25121500
http://dx.doi.org/10.1371/journal.pone.0103044