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The Relationship between Muscle Fiber Type-Specific PGC-1α Content and Mitochondrial Content Varies between Rodent Models and Humans
PGC-1α regulates critical processes in muscle physiology, including mitochondrial biogenesis, lipid metabolism and angiogenesis. Furthermore, PGC-1α was suggested as an important regulator of fiber type determination. However, whether a muscle fiber type-specific PGC-1α content exists, whether PGC-1...
Autores principales: | Gouspillou, Gilles, Sgarioto, Nicolas, Norris, Brandon, Barbat-Artigas, Sébastien, Aubertin-Leheudre, Mylène, Morais, Jose A., Burelle, Yan, Taivassalo, Tanja, Hepple, Russell T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133187/ https://www.ncbi.nlm.nih.gov/pubmed/25121500 http://dx.doi.org/10.1371/journal.pone.0103044 |
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