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Subverting ER-Stress towards Apoptosis by Nelfinavir and Curcumin Coexposure Augments Docetaxel Efficacy in Castration Resistant Prostate Cancer Cells
Despite its side-effects, docetaxel (DTX) remains a first-line treatment against castration resistant prostate cancer (CRPC). Therefore, strategies to increase its anti-tumor efficacy and decrease its side effects are critically needed. Targeting of the constitutive endoplasmic reticulum (ER) stress...
Autores principales: | Mathur, Aditi, Abd Elmageed, Zakaria Y., Liu, Xichun, Kostochka, Mikhail L., Zhang, Haitao, Abdel-Mageed, Asim B., Mondal, Debasis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133210/ https://www.ncbi.nlm.nih.gov/pubmed/25121735 http://dx.doi.org/10.1371/journal.pone.0103109 |
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