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DNA torsion as a feedback mediator of transcription and chromatin dynamics
The double helical structure of DNA lends itself to topological constraints. Many DNA-based processes alter the topological state of DNA, generating torsional stress, which is efficiently relieved by topoisomerases. Maintaining this topological balance is crucial to cell survival, as excessive torsi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133216/ https://www.ncbi.nlm.nih.gov/pubmed/24819949 http://dx.doi.org/10.4161/nucl.29086 |