Cargando…

MicroRNA-30e* Suppresses Dengue Virus Replication by Promoting NF-κB–Dependent IFN Production

MicroRNAs have been shown to contribute to a repertoire of host-pathogen interactions during viral infection. Our previous study demonstrated that microRNA-30e* (miR-30e*) directly targeted the IκBα 3′-UTR and disrupted the NF-κB/IκBα negative feedback loop, leading to hyperactivation of NF-κB. This...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Xun, He, Zhenjian, Hu, Yiwen, Wen, Weitao, Lin, Cuiji, Yu, Jianchen, Pan, Jing, Li, Ran, Deng, Haijing, Liao, Shaowei, Yuan, Jie, Wu, Jueheng, Li, Jun, Li, Mengfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133224/ https://www.ncbi.nlm.nih.gov/pubmed/25122182 http://dx.doi.org/10.1371/journal.pntd.0003088

Ejemplares similares

Bmi-1 Promotes Glioma Angiogenesis by Activating NF-κB Signaling
por: Jiang, Lili, et al.
Publicado: (2013)

A Marine Anthraquinone SZ-685C Overrides Adriamycin-Resistance in Breast Cancer Cells through Suppressing Akt Signaling
por: Zhu, Xun, et al.
Publicado: (2012)

Antibiotic fidaxomicin is an RdRp inhibitor as a potential new therapeutic agent against Zika virus
por: Yuan, Jie, et al.
Publicado: (2020)

Epidemiology characteristics of respiratory viruses found in children and adults with respiratory tract infections in southern China
por: Zhang, Dingmei, et al.
Publicado: (2014)

URGCP promotes non-small cell lung cancer invasiveness by activating the NF-κB-MMP-9 pathway
por: Cai, Junchao, et al.
Publicado: (2015)

AGK enhances angiogenesis and inhibits apoptosis via activation of the NF-κB signaling pathway in hepatocellular carcinoma
por: Cui, Yanmei, et al.
Publicado: (2014)

Bmi-1 promotes the aggressiveness of glioma via activating the NF-kappaB/MMP-9 signaling pathway
por: Jiang, Lili, et al.
Publicado: (2012)

MYEOV functions as an amplified competing endogenous RNA in promoting metastasis by activating TGF-β pathway in NSCLC
por: Fang, Lishan, et al.
Publicado: (2018)

EGF-induced nuclear localization of SHCBP1 activates β-catenin signaling and promotes cancer progression
por: Liu, Lei, et al.
Publicado: (2018)

Zika virus antagonizes interferon response in patients and disrupts RIG-I–MAVS interaction through its CARD-TM domains
por: Hu, Yiwen, et al.
Publicado: (2019)

Overexpression of MACC1 and Its significance in human Breast Cancer Progression
por: Huang, Yongbo, et al.
Publicado: (2013)

SOSTDC1 is down-regulated in non-small cell lung cancer and contributes to cancer cell proliferation
por: Liu, Lei, et al.
Publicado: (2016)

Studies on Synthesis and Structure-Activity Relationship (SAR) of Derivatives of a New Natural Product from Marine Fungi as Inhibitors of Influenza Virus Neuraminidase
por: Li, Jing, et al.
Publicado: (2011)

Duck RIG-I CARD Domain Induces the Chicken IFN-β by Activating NF-κB
por: Chen, Yang, et al.
Publicado: (2015)

NF90 Binds the Dengue Virus RNA 3′ Terminus and Is a Positive Regulator of Dengue Virus Replication
por: Gomila, Raúl C., et al.
Publicado: (2011)

Studies on the Synthesis of Derivatives of Marine-Derived Bostrycin and Their Structure-Activity Relationship against Tumor Cells
por: Chen, Hong, et al.
Publicado: (2012)

Zinc Chelation Specifically Inhibits Early Stages of Dengue Virus Replication by Activation of NF-κB and Induction of Antiviral Response in Epithelial Cells
por: Kar, Meenakshi, et al.
Publicado: (2019)

Alpha-mangostin inhibits viral replication and suppresses nuclear factor kappa B (NF-κB)-mediated inflammation in dengue virus infection
por: Tarasuk, Mayuri, et al.
Publicado: (2022)

Rhinovirus-induced IFNβ expression is NFκB-dependent and regulated by the macrophage microenvironment
por: Menzel, Mandy, et al.
Publicado: (2019)

ISR8/IRF1-AS1 Is Relevant for IFNα and NF-κB Responses
por: Barriocanal, Marina, et al.
Publicado: (2022)

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency
por: Le Voyer, Tom, et al.
Publicado: (2023)

miR-18a Impairs DNA Damage Response through Downregulation of Ataxia Telangiectasia Mutated (ATM) Kinase
por: Song, Libing, et al.
Publicado: (2011)

Sphingosine Kinase 1 Regulates the Akt/FOXO3a/Bim Pathway and Contributes to Apoptosis Resistance in Glioma Cells
por: Guan, Hongyu, et al.
Publicado: (2011)

Cyprinus carpio TRIF Participates in the Innate Immune Response by Inducing NF-κB and IFN Activation and Promoting Apoptosis
por: Liu, Rongrong, et al.
Publicado: (2021)

PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis
por: Tian, Han, et al.
Publicado: (2023)

Activation of Toll-Like Receptor 3 Impairs the Dengue Virus Serotype 2 Replication through Induction of IFN-β in Cultured Hepatoma Cells
por: Liang, Zhaoduan, et al.
Publicado: (2011)

Regulation of NF-κB inhibitor IκBα and viral replication by a KSHV microRNA
por: Lei, Xiufen, et al.
Publicado: (2010)

Regulation of Human Natural Killer Cell IFN-γ Production by MicroRNA-146a via Targeting the NF-κB Signaling Pathway
por: Wang, Hongwei, et al.
Publicado: (2018)

Downregulation of microRNA-221 facilitates H1N1 influenza A virus replication through suppression of type-IFN response by targeting the SOCS1/NF-κB pathway
por: Zhang, Nali, et al.
Publicado: (2021)

IFN-γ Induces Gastric Cancer Cell Proliferation and Metastasis Through Upregulation of Integrin β3-Mediated NF-κB Signaling
por: Xu, Yuan-Hua, et al.
Publicado: (2018)

LIGHT/IFN‐γ triggers β cells apoptosis via NF‐κB/Bcl2‐dependent mitochondrial pathway
por: Zheng, Quan‐You, et al.
Publicado: (2016)

MACC1 as a Prognostic Biomarker for Early-Stage and AFP-Normal Hepatocellular Carcinoma
por: Xie, Chan, et al.
Publicado: (2013)

Aberrantly expressed miR-582-3p maintains lung cancer stem cell-like traits by activating Wnt/β-catenin signalling
por: Fang, Lishan, et al.
Publicado: (2015)

Long noncoding RNA LINC00673-v4 promotes aggressiveness of lung adenocarcinoma via activating WNT/β-catenin signaling
por: Guan, Hongyu, et al.
Publicado: (2019)

Loss of ATF4 leads to functional aging-like attrition of adult hematopoietic stem cells
por: Sun, Yan, et al.
Publicado: (2021)

PEDV ORF3 Independently Regulates IκB Kinase β-Mediated NF-κB and IFN-β Promoter Activities
por: Kaewborisuth, Challika, et al.
Publicado: (2020)

Cirsimaritin inhibits influenza A virus replication by downregulating the NF-κB signal transduction pathway
por: Yan, Haiyan, et al.
Publicado: (2018)

Isorhamnetin Induces Melanoma Cell Apoptosis via the PI3K/Akt and NF-κB Pathways
por: Duan, Ran, et al.
Publicado: (2020)

Signal Integration of IFN-I and IFN-II With TLR4 Involves Sequential Recruitment of STAT1-Complexes and NFκB to Enhance Pro-inflammatory Transcription
por: Piaszyk-Borychowska, Anna, et al.
Publicado: (2019)

IFN-τ Displays Anti-Inflammatory Effects on Staphylococcus aureus Endometritis via Inhibiting the Activation of the NF-κB and MAPK Pathways in Mice
por: Zhang, Zhenbiao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_d25m88rdrjfat9v7kg4lsfis7t