Diverse Expression of Selected SMN Complex Proteins in Humans with Sporadic Amyotrophic Lateral Sclerosis and in a Transgenic Rat Model of Familial Form of the Disease

BACKGROUND AND OBJECTIVE: There is circumstantial evidence linking sporadic amyotrophic lateral sclerosis (ALS) cases to a malfunction or deficit of a multimeric SMN complex that scrutinizes cellular RNAs; the core of this complex is survival motor neuron (SMN, or gemin 1) protein. We intended to ve...

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Detalles Bibliográficos
Autores principales: Rafałowska, Janina, Sulejczak, Dorota, Chrapusta, Stanisław J., Gadamski, Roman, Dziewulska, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133261/
https://www.ncbi.nlm.nih.gov/pubmed/25122454
http://dx.doi.org/10.1371/journal.pone.0104614

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