Cargando…
EBNA3C Augments Pim-1 Mediated Phosphorylation and Degradation of p21 to Promote B-Cell Proliferation
Epstein–Barr virus (EBV), a ubiquitous human herpesvirus, can latently infect the human population. EBV is associated with several types of malignancies originating from lymphoid and epithelial cell types. EBV latent antigen 3C (EBNA3C) is essential for EBV-induced immortalization of B-cells. The Mo...
Autores principales: | Banerjee, Shuvomoy, Lu, Jie, Cai, Qiliang, Sun, Zhiguo, Jha, Hem Chandra, Robertson, Erle S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133388/ https://www.ncbi.nlm.nih.gov/pubmed/25121590 http://dx.doi.org/10.1371/journal.ppat.1004304 |
Ejemplares similares
-
Dissecting the contribution of EBNA3C domains important for EBV-induced B-cell growth and proliferation
por: Jha, Hem Chandra, et al.
Publicado: (2015) -
An essential EBV latent antigen 3C binds Bcl6 for targeted degradation and cell proliferation
por: Pei, Yonggang, et al.
Publicado: (2017) -
EBV Nuclear Antigen 3C Mediates Regulation of E2F6 to Inhibit E2F1 Transcription and Promote Cell Proliferation
por: Pei, Yonggang, et al.
Publicado: (2016) -
The Role of Gammaherpesviruses in Cancer Pathogenesis
por: Jha, Hem Chandra, et al.
Publicado: (2016) -
The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8
por: Banerjee, Shuvomoy, et al.
Publicado: (2013)