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EVM005: An Ectromelia-Encoded Protein with Dual Roles in NF-κB Inhibition and Virulence

Poxviruses contain large dsDNA genomes encoding numerous open reading frames that manipulate cellular signalling pathways and interfere with the host immune response. The NF-κB signalling cascade is an important mediator of innate immunity and inflammation, and is tightly regulated by ubiquitination...

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Detalles Bibliográficos
Autores principales:	van Buuren, Nicholas, Burles, Kristin, Schriewer, Jill, Mehta, Ninad, Parker, Scott, Buller, R. Mark, Barry, Michele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133408/ https://www.ncbi.nlm.nih.gov/pubmed/25122471 http://dx.doi.org/10.1371/journal.ppat.1004326

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