Efficient and cost effective production of active-form human PKB using silkworm larvae

Protein kinase B (PKB) also known as Akt is involved in many signal transduction pathways. As alterations of the PKB pathway are found in a number of human malignancies, PKB is considered an important drug target for cancer therapy. However, production of sufficient amounts of active PKB for biochem...

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Detalles Bibliográficos
Autores principales: Maesaki, Ryoko, Satoh, Ryosuke, Taoka, Masato, Kanaba, Teppei, Asano, Tsunaki, Fujita, Chiharu, Fujiwara, Toshinobu, Ito, Yutaka, Isobe, Toshiaki, Hakoshima, Toshio, Maenaka, Katsumi, Mishima, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133716/
https://www.ncbi.nlm.nih.gov/pubmed/25125290
http://dx.doi.org/10.1038/srep06016

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