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Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells
Occludin is the first identified protein in the tight junction (TJ), but its function has remained for the most part obscure. TJs have been demonstrated to play important roles in the inner ear function, and occludin is expressed in all the epithelial TJs in the inner ear. Thus, we examined the inne...
Autores principales: | Kitajiri, Shin-ichiro, Katsuno, Tatsuya, Sasaki, Hiroyuki, Ito, Juichi, Furuse, Mikio, Tsukita, Shoichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133728/ https://www.ncbi.nlm.nih.gov/pubmed/25063198 http://dx.doi.org/10.1242/bio.20147799 |
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