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Link between Primate Lentiviral Coreceptor Usage and Nef Function

Simian immunodeficiency virus (SIVsmm) infection of sooty mangabeys (Cercocebus atys) is characterized by stable CD4(+) T cell counts despite high plasma levels of CCR5-tropic viruses. However, in rare instances, SIVsmm acquires CXCR4 coreceptor tropism and causes severe CD4(+) T cell depletion, alb...

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Detalles Bibliográficos
Autores principales:	Schmökel, Jan, Li, Hui, Shabir, Asma, Yu, Hangxing, Geyer, Matthias, Silvestri, Guido, Sodora, Donald L., Hahn, Beatrice H., Kirchhoff, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133736/ https://www.ncbi.nlm.nih.gov/pubmed/24268781 http://dx.doi.org/10.1016/j.celrep.2013.10.028

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