Proteomic Revelations

The power of proteomics in cultured skin fibroblasts from individuals both systemic sclerosis and recessive dystrophic epidermolysis bullosa has led to the common finding of senescence and deficiencies in autophagy. Both of these disorders exert high demand on fibroblast activity, and without the pr...

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Detalles Bibliográficos
Autor principal: Davidson, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133747/
https://www.ncbi.nlm.nih.gov/pubmed/25120144
http://dx.doi.org/10.1038/jid.2014.242
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author Davidson, Jeffrey M.
author_facet Davidson, Jeffrey M.
author_sort Davidson, Jeffrey M.
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description The power of proteomics in cultured skin fibroblasts from individuals both systemic sclerosis and recessive dystrophic epidermolysis bullosa has led to the common finding of senescence and deficiencies in autophagy. Both of these disorders exert high demand on fibroblast activity, and without the protective action of autophagy, cellular stress could have many adverse effects that are further amplified by the senescent phenotype.
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spelling pubmed-41337472015-03-01 Proteomic Revelations Davidson, Jeffrey M. J Invest Dermatol Article The power of proteomics in cultured skin fibroblasts from individuals both systemic sclerosis and recessive dystrophic epidermolysis bullosa has led to the common finding of senescence and deficiencies in autophagy. Both of these disorders exert high demand on fibroblast activity, and without the protective action of autophagy, cellular stress could have many adverse effects that are further amplified by the senescent phenotype. 2014-09 /pmc/articles/PMC4133747/ /pubmed/25120144 http://dx.doi.org/10.1038/jid.2014.242 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Davidson, Jeffrey M.
Proteomic Revelations
title Proteomic Revelations
title_full Proteomic Revelations
title_fullStr Proteomic Revelations
title_full_unstemmed Proteomic Revelations
title_short Proteomic Revelations
title_sort proteomic revelations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133747/
https://www.ncbi.nlm.nih.gov/pubmed/25120144
http://dx.doi.org/10.1038/jid.2014.242
work_keys_str_mv AT davidsonjeffreym proteomicrevelations

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