Immunoprecipitation and mass spectrometry identify non-cell autonomous Otx2 homeoprotein in the granular and supragranular layers of mouse visual cortex

Plasticity in the visual cerebral cortex is regulated by the internalization of Otx2 homeoprotein into parvalbumin neurons in cortical layers II/III and IV. However the Otx2 locus is not active in these neurons and the protein is imported from external sources, including the choroid plexus. Because...

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Detalles Bibliográficos
Autores principales: Kim, Namsuk, Acampora, Dario, Dingli, Florent, Loew, Damarys, Simeone, Antonio, Prochiantz, Alain, Di Nardo, Ariel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133762/
https://www.ncbi.nlm.nih.gov/pubmed/25165539
http://dx.doi.org/10.12688/f1000research.4869.1

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