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Expression level and glycan dynamics determine the net effects of TIMP-1 on cancer progression

Tissue inhibitor of metalloproteinases (TIMPs; TIMP-1, -2, -3 and -4) are endogenous inhibitor for matrix metalloproteinases (MMPs) that are responsible for remodeling the extracellular matrix (ECM) and involved in migration, invasion and metastasis of tumor cells. Unlike under normal conditions, th...

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Detalles Bibliográficos
Autores principales: Kim, Yong-Sam, Kim, Sun-Hee, Kang, Jeong-Gu, Ko, Jeong-Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133808/
https://www.ncbi.nlm.nih.gov/pubmed/23187000
http://dx.doi.org/10.5483/BMBRep.2012.45.11.233

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