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Roles of cysteine residues in the inhibition of human glutamate dehydrogenase by palmitoyl-CoA

Human glutamate dehydrogenase isozymes (hGDH1 and hGDH2) have been known to be inhibited by palmitoyl-CoA with a high affinity. In this study, we have performed the cassette mutagenesis at six different Cys residues (Cys59, Cys93, Cys119, Cys201, Cys274, and Cys323) to identify palmitoyl-CoA binding...

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Detalles Bibliográficos
Autores principales:	Son, Hyo Jeong, Ha, Seung Cheol, Hwang, Eun Young, Kim, Eun-A, Ahn, Jee-Yin, Choi, Soo Young, Cho, Sung-Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133811/ https://www.ncbi.nlm.nih.gov/pubmed/23261056 http://dx.doi.org/10.5483/BMBRep.2012.45.12.156

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