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Egr-1 regulates the transcription of the BRCA1 gene by etoposide

The breast cancer susceptibility gene BRCA1 encodes a nuclear protein, which functions as a tumor suppressor and is involved in gene transcription and DNA repair processes. Many families with inherited breast and ovarian cancers have mutations in the BRCA1 gene. However, only a few studies have repo...

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Detalles Bibliográficos
Autores principales: Shin, Soon Young, Kim, Chang Gun, Lee, Young Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133847/
https://www.ncbi.nlm.nih.gov/pubmed/23433111
http://dx.doi.org/10.5483/BMBRep.2013.46.2.202