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Elevated RalA activity in the hippocampus of PI3Kγ knock-out mice lacking NMDAR-dependent long-term depression

Phosphoinositide 3-kinases (PI3Ks) play key roles in synaptic plasticity and cognitive functions in the brain. We recently found that genetic deletion of PI3Kγ, the only known member of class IB PI3Ks, results in impaired N-methyl-(D)-aspartate receptor-dependent long-term depression (NMDAR-LTD) in...

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Detalles Bibliográficos
Autores principales:	Sim, Su-Eon, Lee, Hye-Ryeon, Kim, Jae-Ick, Choi, Sun-Lim, Bakes, Joseph, Jang, Deok-Jin, Lee, Kyungmin, Han, Kihoon, Kim, Eunjoon, Kaang, Bong-Kiun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133848/ https://www.ncbi.nlm.nih.gov/pubmed/23433113 http://dx.doi.org/10.5483/BMBRep.2013.46.2.143

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