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Mouse models of polycystic kidney disease induced by defects of ciliary proteins
Polycystic kidney disease (PKD) is a common hereditary disorder which is characterized by fluid-filled cysts in the kidney. Mutation in either PKD1, encoding polycystin-1 (PC1), or PKD2, encoding polycystin-2 (PC2), are causative genes of PKD. Recent studies indicate that renal cilia, known as mecha...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133850/ https://www.ncbi.nlm.nih.gov/pubmed/23433108 http://dx.doi.org/10.5483/BMBRep.2013.46.2.022 |