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Detection of rare point mutation via allele-specific amplification in emulsion PCR
It is essential to analyze rare mutations in many fields of biomedical research. However, the detection of rare mutations is usually failed due to the interference of predominant wild-type DNA surrounded. Herein we describe a sensitive and facile method of detecting rare point mutation on the basis...
Autores principales: | Cheng, Changming, Zhou, Yin, Yang, Chao, Chen, Juan, Wang, Jie, Zhang, Jie, Zhao, Guoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133893/ https://www.ncbi.nlm.nih.gov/pubmed/23710638 http://dx.doi.org/10.5483/BMBRep.2013.46.5.155 |
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