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Reactive Oxygen Species (ROS) Inducible DNA Cross-Linking Agents and Their Effect on Cancer Cells and Normal Lymphocytes

[Image: see text] Reducing host toxicity is one of the main challenges of cancer chemotherapy. Many tumor cells contain high levels of ROS that make them distinctively different from normal cells. We report a series of ROS-activated aromatic nitrogen mustards that selectively kill chronic lymphocyti...

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Detalles Bibliográficos
Autores principales:	Chen, Wenbing, Balakrishnan, Kumudha, Kuang, Yunyan, Han, Yanyan, Fu, Min, Gandhi, Varsha, Peng, Xiaohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133937/ https://www.ncbi.nlm.nih.gov/pubmed/24801734 http://dx.doi.org/10.1021/jm401349g

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