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Crystal Structure of a Complex of NOD1 CARD and Ubiquitin

The Caspase Recruitment Domain (CARD) from the innate immune receptor NOD1 was crystallized with Ubiquitin (Ub). NOD1 CARD was present as a helix-swapped homodimer similar to other structures of NOD1 CARD, and Ub monomers formed a homodimer similar in conformation to Lys48-linked di-Ub. The interact...

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Detalles Bibliográficos
Autores principales:	Ver Heul, Aaron M., Gakhar, Lokesh, Piper, Robert C., Subramanian, Ramaswamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134136/ https://www.ncbi.nlm.nih.gov/pubmed/25127239 http://dx.doi.org/10.1371/journal.pone.0104017

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