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Loss of Intralipid®- but Not Sevoflurane-Mediated Cardioprotection in Early Type-2 Diabetic Hearts of Fructose-Fed Rats: Importance of ROS Signaling

BACKGROUND: Insulin resistance and early type-2 diabetes are highly prevalent. However, it is unknown whether Intralipid® and sevoflurane protect the early diabetic heart against ischemia-reperfusion injury. METHODS: Early type-2 diabetic hearts from Sprague-Dawley rats fed for 6 weeks with fructose...

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Detalles Bibliográficos
Autores principales: Lou, Phing-How, Lucchinetti, Eliana, Zhang, Liyan, Affolter, Andreas, Gandhi, Manoj, Hersberger, Martin, Warren, Blair E., Lemieux, Hélène, Sobhi, Hany F., Clanachan, Alexander S., Zaugg, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134246/
https://www.ncbi.nlm.nih.gov/pubmed/25127027
http://dx.doi.org/10.1371/journal.pone.0104971