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Inhibition of c-Myc Overcomes Cytotoxic Drug Resistance in Acute Myeloid Leukemia Cells by Promoting Differentiation

Nowadays, drug resistance still represents a major obstacle to successful acute myeloid leukemia (AML) treatment and the underlying mechanism is not fully elucidated. Here, we found that high expression of c-Myc was one of the cytogenetic characteristics in the drug-resistant leukemic cells. c-Myc o...

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Detalles Bibliográficos
Autores principales:	Pan, Xiao-Na, Chen, Jia-Jie, Wang, Le-Xun, Xiao, Ruo-Zhi, Liu, Ling-Ling, Fang, Zhi-Gang, Liu, Quentin, Long, Zi-Jie, Lin, Dong-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134294/ https://www.ncbi.nlm.nih.gov/pubmed/25127121 http://dx.doi.org/10.1371/journal.pone.0105381

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