Cargando…

The role of TGF-β1–miR-21–ROS pathway in bystander responses induced by irradiated non-small-cell lung cancer cells

BACKGROUND: Many studies have indicated an important implication of radiation-induced bystander effects (RIBEs) in cancer radiotherapy, but the detailed signalling remains unclear. METHODS: The roles of tumour growth factor-beta1 (TGF-β1) and miR-21 in medium-mediated RIBEs in H1299 non-small-cell l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Y, Chen, X, Tian, W, Yin, X, Wang, J, Yang, H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134503/ https://www.ncbi.nlm.nih.gov/pubmed/24992582 http://dx.doi.org/10.1038/bjc.2014.368

Ejemplares similares

Cytochrome-c mediated a bystander response dependent on inducible nitric oxide synthase in irradiated hepatoma cells
por: He, M, et al.
Publicado: (2012)

Downregulation of miR-302c and miR-520c by 1,25(OH)2D3 treatment enhances the susceptibility of tumour cells to natural killer cell-mediated cytotoxicity
por: Min, D, et al.
Publicado: (2013)

miR-367 promotes epithelial-to-mesenchymal transition and invasion of pancreatic ductal adenocarcinoma cells by targeting the Smad7-TGF-β signalling pathway
por: Zhu, Z, et al.
Publicado: (2015)

Predictive value of miR-9 as a potential biomarker for nasopharyngeal carcinoma metastasis
por: Lu, J, et al.
Publicado: (2014)

MiR-224 promotes the chemoresistance of human lung adenocarcinoma cells to cisplatin via regulating G(1)/S transition and apoptosis by targeting p21(WAF1/CIP1)
por: Wang, H, et al.
Publicado: (2014)

miR-21 and miR-155 are associated with mitotic activity and lesion depth of borderline melanocytic lesions
por: Grignol, V, et al.
Publicado: (2011)

Cancer-associated fibroblasts induce epithelial–mesenchymal transition of breast cancer cells through paracrine TGF-β signalling
por: Yu, Y, et al.
Publicado: (2014)

MicroRNA expression profiling identifies miR-328 regulates cancer stem cell-like SP cells in colorectal cancer
por: Xu, X T, et al.
Publicado: (2012)

miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer
por: Zhang, J, et al.
Publicado: (2012)

MiR-125b acts as an oncogene in glioblastoma cells and inhibits cell apoptosis through p53 and p38MAPK-independent pathways
por: Wu, N, et al.
Publicado: (2013)

MiR-646 inhibited cell proliferation and EMT-induced metastasis by targeting FOXK1 in gastric cancer
por: Zhang, P, et al.
Publicado: (2017)

Chemoresistant colorectal cancer cells and cancer stem cells mediate growth and survival of bystander cells
por: Bose, D, et al.
Publicado: (2011)

High expression of kinesin light chain-2, a novel target of miR-125b, is associated with poor clinical outcome of elderly non-small-cell lung cancer patients
por: Wang, M, et al.
Publicado: (2015)

TAp63 suppress metastasis via miR-133b in colon cancer cells
por: Lin, C W, et al.
Publicado: (2014)

MiR-204 inhibits human NSCLC metastasis through suppression of NUAK1
por: Shi, L, et al.
Publicado: (2014)

miR-1228 promotes the proliferation and metastasis of hepatoma cells through a p53 forward feedback loop
por: Zhang, Y, et al.
Publicado: (2015)

Direct targeting of SUZ12/ROCK2 by miR-200b/c inhibits cholangiocarcinoma tumourigenesis and metastasis
por: Peng, F, et al.
Publicado: (2013)

Restoration of TGF-β signalling reduces tumorigenicity in human lung cancer cells
por: Anumanthan, G, et al.
Publicado: (2005)

Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients
por: Meng, Xiaodan, et al.
Publicado: (2015)

Radiation quality-dependence of bystander effect in unirradiated fibroblasts is associated with TGF-β1-Smad2 pathway and miR-21 in irradiated keratinocytes
por: Yin, Xiaoming, et al.
Publicado: (2015)

Upregulation of cancer-associated myofibroblasts by TGF-β from scirrhous gastric carcinoma cells
por: Fuyuhiro, Y, et al.
Publicado: (2011)

The oncomiR miR-197 is a novel prognostic indicator for non-small cell lung cancer patients
por: Mavridis, K, et al.
Publicado: (2015)

Overexpression of FOXG1 contributes to TGF-β resistance through inhibition of p21(WAF1/CIP1) expression in ovarian cancer
por: Chan, D W, et al.
Publicado: (2009)

TGFβ-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cells
por: Mu, Y, et al.
Publicado: (2015)

Downregulated miR-646 in clear cell renal carcinoma correlated with tumour metastasis by targeting the nin one binding protein (NOB1)
por: Li, W, et al.
Publicado: (2014)

Fucosylated TGF-β receptors transduces a signal for epithelial–mesenchymal transition in colorectal cancer cells
por: Hirakawa, M, et al.
Publicado: (2014)

Connexins and cyclooxygenase-2 crosstalk in the expression of radiation-induced bystander effects
por: Zhao, Y, et al.
Publicado: (2014)

Metadherin regulates proliferation and metastasis via actin cytoskeletal remodelling in non-small cell lung cancer
por: Yao, Y, et al.
Publicado: (2014)

Cyclooxygenase-2 overexpression abrogates the antiproliferative effects of TGF-β
por: Enders, G A
Publicado: (2007)

miRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215
por: White, N M A, et al.
Publicado: (2011)

Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer
por: Huh, J H, et al.
Publicado: (2013)

The tumour suppressor miR-34c targets MET in prostate cancer cells
por: Hagman, Z, et al.
Publicado: (2013)

Prognostic and diagnostic potential of miR-146a in oesophageal squamous cell carcinoma
por: Wang, Cong, et al.
Publicado: (2016)

Mitochondria-dependent signalling pathway are involved in the early process of radiation-induced bystander effects
por: Chen, S, et al.
Publicado: (2008)

Inhibition of TGF-β and EGF pathway gene expression and migration of oral carcinoma cells by mucosa-associated lymphoid tissue 1
por: Ohyama, Y, et al.
Publicado: (2013)

WW domain binding protein 5 induces multidrug resistance of small cell lung cancer under the regulation of miR-335 through the Hippo pathway
por: Tang, Ruixiang, et al.
Publicado: (2016)

Differential expression of microRNAs during melanoma progression: miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors
por: Xu, Y, et al.
Publicado: (2012)

The FOXD3/miR-214/MED19 axis suppresses tumour growth and metastasis in human colorectal cancer
por: He, G Y, et al.
Publicado: (2016)

miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC)
por: Kikkawa, N, et al.
Publicado: (2010)

SERPINB3 is associated with TGF-β1 and cytoplasmic β-catenin expression in hepatocellular carcinomas with poor prognosis
por: Turato, C, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_0ut3pmn1chbfdtia7nu0dssfbk