Cargando…

L-leucine, beta-hydroxy-beta-methylbutyric acid (HMB) and creatine monohydrate prevent myostatin-induced Akirin-1/Mighty mRNA down-regulation and myotube atrophy

BACKGROUND: The purpose of this study was to examine if L-leucine (Leu), β-hydroxy-β-methylbutyrate (HMB), or creatine monohydrate (Crea) prevented potential atrophic effects of myostatin (MSTN) on differentiated C2C12 myotubes. METHODS: After four days of differentiation, myotubes were treated with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mobley, Christopher Brooks, Fox, Carlton D, Ferguson, Brian S, Amin, Rajesh H, Dalbo, Vincent J, Baier, Shawn, Rathmacher, John A, Wilson, Jacob M, Roberts, Michael D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134516/ https://www.ncbi.nlm.nih.gov/pubmed/25132809 http://dx.doi.org/10.1186/1550-2783-11-38

Ejemplares similares

Acute and timing effects of beta-hydroxy-beta-methylbutyrate (HMB) on indirect markers of skeletal muscle damage
por: Wilson, Jacob M, et al.
Publicado: (2009)

The impact of acute beta-hydroxy-beta-methylbutyrate (HMB) ingestion on glucose and insulin kinetics in young and older men
por: Herrod, Philip J.J., et al.
Publicado: (2020)

International Society of Sports Nutrition Position Stand: beta-hydroxy-beta-methylbutyrate (HMB)
por: Wilson, Jacob M, et al.
Publicado: (2013)

The addition of β-Hydroxy β-Methylbutyrate (HMB) to creatine monohydrate supplementation does not improve anthropometric and performance maintenance across a collegiate rugby season
por: Mangine, Gerald T., et al.
Publicado: (2020)

Mechanism of Action and the Effect of Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation on Different Types of Physical Performance - A Systematic Review
por: Kaczka, Piotr, et al.
Publicado: (2019)

Evaluation of Feeding Beta-Hydroxy-Beta-Methylbutyrate (HMB) to Mouse Dams during Gestation on Birth Weight and Growth Variation of Offspring
por: Clarke, Anna S., et al.
Publicado: (2023)

Bone mineral density changes of lumbar spine and femur in osteoporotic patient treated with bisphosphonates and beta-hydroxy-beta-methylbutyrate (HMB): Case report
por: Tatara, Marcin R., et al.
Publicado: (2017)

Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review
por: Wilson, Gabriel J, et al.
Publicado: (2008)

Long-Term Effect of Combination of Creatine Monohydrate Plus β-Hydroxy β-Methylbutyrate (HMB) on Exercise-Induced Muscle Damage and Anabolic/Catabolic Hormones in Elite Male Endurance Athletes
por: Fernández-Landa, Julen, et al.
Publicado: (2020)

Dual Effects of Beta-Hydroxy-Beta-Methylbutyrate (HMB) on Amino Acid, Energy, and Protein Metabolism in the Liver and Muscles of Rats with Streptozotocin-Induced Type 1 Diabetes
por: Holeček, Milan, et al.
Publicado: (2020)

Effects of 12 weeks of beta-hydroxy-beta-methylbutyrate free acid gel supplementation on muscle mass, strength, and power in resistance trained individuals
por: Dunsmore, KA, et al.
Publicado: (2012)

Effect of Oral Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation on Physical Performance in Healthy Old Women Over 65 Years: An Open Label Randomized Controlled Trial
por: Berton, Linda, et al.
Publicado: (2015)

Effects of 12 weeks of beta-hydroxy-beta-methylbutyrate free acid, adenosine triphosphate, or a combination on muscle mass, strength, and power in resistance trained individuals
por: Lowery, Ryan P, et al.
Publicado: (2013)

Produced β-hydroxybutyrate after β-hydroxy-β-methylbutyrate (HMB) administration may contribute HMB function in mice
por: Ikeda, Kazuki, et al.
Publicado: (2021)

The Effect of a 12-Week Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation on Highly-Trained Combat Sports Athletes: A Randomised, Double-Blind, Placebo-Controlled Crossover Study
por: Durkalec-Michalski, Krzysztof, et al.
Publicado: (2017)

The effects of beta-hydoxy-beta-methylbutyrate free acid supplementation on muscle damage, hormonal status, and performance following a high volume 2-week overreaching cycle
por: Davis, GS, et al.
Publicado: (2012)

The influence of dietary supplementation with the leucine metabolite β-hydroxy-β-methylbutyrate (HMB) on the chemotaxis, phagocytosis and respiratory burst of peripheral blood granulocytes and monocytes in calves
por: Wójcik, Roman, et al.
Publicado: (2020)

Effect of Ten Weeks of Creatine Monohydrate Plus HMB Supplementation on Athletic Performance Tests in Elite Male Endurance Athletes
por: Fernández-Landa, Julen, et al.
Publicado: (2020)

Myostatin Suppression of Akirin1 Mediates Glucocorticoid-Induced Satellite Cell Dysfunction
por: Dong, Yanjun, et al.
Publicado: (2013)

Beta-hydroxy beta-methylbutyrate/arginine/glutamine (HMB/Arg/Gln) supplementation to improve the management of cachexia in patients with advanced lung cancer: an open-label, multicentre, randomised, controlled phase II trial (NOURISH)
por: Pascoe, Jennifer, et al.
Publicado: (2021)

β-Hydroxy-β-Methylbutyrate (HMB) Promotes Neurite Outgrowth in Neuro2a Cells
por: Salto, Rafael, et al.
Publicado: (2015)

Characterisation of equine satellite cell transcriptomic profile response to β-hydroxy-β-methylbutyrate (HMB)
por: Szcześniak, Katarzyna A., et al.
Publicado: (2016)

Randomized Clinical Trial: Effects of β-Hydroxy-β-Methylbutyrate (HMB)-Enriched vs. HMB-Free Oral Nutritional Supplementation in Malnourished Cirrhotic Patients
por: Espina, Silvia, et al.
Publicado: (2022)

The effects of 12 weeks of beta-hydroxy-beta-methylbutyrate free acid supplementation on muscle mass, strength, and power in resistance-trained individuals: a randomized, double-blind, placebo-controlled study
por: Wilson, Jacob M., et al.
Publicado: (2014)

β-Hydroxy-β-Methylbutyrate (HMB) Normalizes Dexamethasone-Induced Autophagy-Lysosomal Pathway in Skeletal Muscle
por: Girón, María D., et al.
Publicado: (2015)

Effect of β-hydroxy-β-methylbutyrate (HMB) on the Muscle Strength in the Elderly Population: A Meta-Analysis
por: Lin, Ziru, et al.
Publicado: (2022)

Beta‐hydroxy‐beta‐methylbutyrate supplementation and skeletal muscle in healthy and muscle‐wasting conditions
por: Holeček, Milan
Publicado: (2017)

Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism
por: Wilkinson, D J, et al.
Publicado: (2013)

Supplementation with the Leucine Metabolite β-hydroxy-β-methylbutyrate (HMB) does not Improve Resistance Exercise-Induced Changes in Body Composition or Strength in Young Subjects: A Systematic Review and Meta-Analysis
por: Jakubowski, Josephine S., et al.
Publicado: (2020)

Effect of the Combination of Creatine Monohydrate Plus HMB Supplementation on Sports Performance, Body Composition, Markers of Muscle Damage and Hormone Status: A Systematic Review
por: Fernández-Landa, Julen, et al.
Publicado: (2019)

Acute anabolic response to β-hydroxy-β-methylbutyrate (HMB)-free acid supplementation following heavy resistance exercise
por: Townsend, JR, et al.
Publicado: (2014)

The Effects of β-Hydroxy-β-Methylbutyrate (HMB) on Chemotaxis, Phagocytosis, and Oxidative Burst of Peripheral Blood Granulocytes and Monocytes in Goats
por: Wójcik, Roman, et al.
Publicado: (2019)

Conversion of leucine to β‐hydroxy‐β‐methylbutyrate by α‐keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes
por: Girón, María D., et al.
Publicado: (2015)

Effects of combined β-hydroxy-β-methylbutyrate (HMB) and whey protein ingestion on symptoms of eccentric exercise-induced muscle damage
por: Shirato, Minayuki, et al.
Publicado: (2016)

Cellular and Physiological Effects of Dietary Supplementation with β-Hydroxy-β-Methylbutyrate (HMB) and β-Alanine in Late Middle-Aged Mice
por: Vallejo, Julian, et al.
Publicado: (2016)

Research Note: Creatine monohydrate alleviates protein breakdown induced by corticosterone via inhibiting ubiquitin proteasome pathway in chicken myotubes
por: Sun, Mingfa, et al.
Publicado: (2022)

Effects of six-month supplementation with beta-hydroxy-beta-methylbutyrate, glutamine, and arginine on vascular endothelial function of older adults
por: Ellis, Amy, et al.
Publicado: (2015)

Effects of combined maternal administration with alpha-ketoglutarate (AKG) and β-hydroxy-β-methylbutyrate (HMB) on prenatal programming of skeletal properties in the offspring
por: Tatara, Marcin R, et al.
Publicado: (2012)

Effects of β‐hydroxy β‐methylbutyrate (HMB) supplementation on muscle mass, function, and other outcomes in patients with cancer: a systematic review
por: Prado, Carla M., et al.
Publicado: (2022)

Effect of Resistance Training Combined with Beta‐Hydroxy‐Beta‐Methylbutyric Acid Supplements in Elderly Patients with Sarcopenia after Hip Replacement
por: Han, Zhe, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9v2bjqv8htunl3e31lae8npn3j