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Elevated YKL40 is associated with advanced prostate cancer (PCa) and positively regulates invasion and migration of PCa cells

Chitinase 3-like 1 (CHI3L1 or YKL40) is a secreted glycoprotein highly expressed in tumours from patients with advanced stage cancers, including prostate cancer (PCa). The exact function of YKL40 is poorly understood, but it has been shown to play an important role in promoting tumour angiogenesis a...

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Detalles Bibliográficos
Autores principales: Jeet, Varinder, Tevz, Gregor, Lehman, Melanie, Hollier, Brett, Nelson, Colleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134518/
https://www.ncbi.nlm.nih.gov/pubmed/24981110
http://dx.doi.org/10.1530/ERC-14-0267