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Management of Infantile Hemangiomas: Current Trends

Infantile hemangiomas (IH) are common vascular tumours. IH have a characteristic natural course. They proliferate rapidly during the early infantile period followed by a period of gradual regression over several years. Most of the uncomplicated IH undergo spontaneous involution, with a small proport...

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Autores principales: Sethuraman, Gomathy, Yenamandra, Vamsi K, Gupta, Vishal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134656/
https://www.ncbi.nlm.nih.gov/pubmed/25136206
http://dx.doi.org/10.4103/0974-2077.138324
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author Sethuraman, Gomathy
Yenamandra, Vamsi K
Gupta, Vishal
author_facet Sethuraman, Gomathy
Yenamandra, Vamsi K
Gupta, Vishal
author_sort Sethuraman, Gomathy
collection PubMed
description Infantile hemangiomas (IH) are common vascular tumours. IH have a characteristic natural course. They proliferate rapidly during the early infantile period followed by a period of gradual regression over several years. Most of the uncomplicated IH undergo spontaneous involution, with a small proportion of cases requiring intervention. These are children with IH in life-threatening locations, local complications like haemorrhage, ulceration and necrosis and functional or cosmetic disfigurements. Systemic corticosteroids have been the first line of treatment for many years. Recently, non-selective beta-blockers, such as oral propranalol and topical timolol, have emerged as promising and safer therapies. Other treatment options include interferon α and vincristine which are reserved for life-threatening haemangiomas that are unresponsive to conventional therapy. This review mainly focuses on the current trends and evidence-based approach in the management of IH.
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spelling pubmed-41346562014-08-18 Management of Infantile Hemangiomas: Current Trends Sethuraman, Gomathy Yenamandra, Vamsi K Gupta, Vishal J Cutan Aesthet Surg CME Article Infantile hemangiomas (IH) are common vascular tumours. IH have a characteristic natural course. They proliferate rapidly during the early infantile period followed by a period of gradual regression over several years. Most of the uncomplicated IH undergo spontaneous involution, with a small proportion of cases requiring intervention. These are children with IH in life-threatening locations, local complications like haemorrhage, ulceration and necrosis and functional or cosmetic disfigurements. Systemic corticosteroids have been the first line of treatment for many years. Recently, non-selective beta-blockers, such as oral propranalol and topical timolol, have emerged as promising and safer therapies. Other treatment options include interferon α and vincristine which are reserved for life-threatening haemangiomas that are unresponsive to conventional therapy. This review mainly focuses on the current trends and evidence-based approach in the management of IH. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4134656/ /pubmed/25136206 http://dx.doi.org/10.4103/0974-2077.138324 Text en Copyright: © Journal of Cutaneous and Aesthetic Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle CME Article
Sethuraman, Gomathy
Yenamandra, Vamsi K
Gupta, Vishal
Management of Infantile Hemangiomas: Current Trends
title Management of Infantile Hemangiomas: Current Trends
title_full Management of Infantile Hemangiomas: Current Trends
title_fullStr Management of Infantile Hemangiomas: Current Trends
title_full_unstemmed Management of Infantile Hemangiomas: Current Trends
title_short Management of Infantile Hemangiomas: Current Trends
title_sort management of infantile hemangiomas: current trends
topic CME Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134656/
https://www.ncbi.nlm.nih.gov/pubmed/25136206
http://dx.doi.org/10.4103/0974-2077.138324
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