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Management of Infantile Hemangiomas: Current Trends
Infantile hemangiomas (IH) are common vascular tumours. IH have a characteristic natural course. They proliferate rapidly during the early infantile period followed by a period of gradual regression over several years. Most of the uncomplicated IH undergo spontaneous involution, with a small proport...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134656/ https://www.ncbi.nlm.nih.gov/pubmed/25136206 http://dx.doi.org/10.4103/0974-2077.138324 |
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author | Sethuraman, Gomathy Yenamandra, Vamsi K Gupta, Vishal |
author_facet | Sethuraman, Gomathy Yenamandra, Vamsi K Gupta, Vishal |
author_sort | Sethuraman, Gomathy |
collection | PubMed |
description | Infantile hemangiomas (IH) are common vascular tumours. IH have a characteristic natural course. They proliferate rapidly during the early infantile period followed by a period of gradual regression over several years. Most of the uncomplicated IH undergo spontaneous involution, with a small proportion of cases requiring intervention. These are children with IH in life-threatening locations, local complications like haemorrhage, ulceration and necrosis and functional or cosmetic disfigurements. Systemic corticosteroids have been the first line of treatment for many years. Recently, non-selective beta-blockers, such as oral propranalol and topical timolol, have emerged as promising and safer therapies. Other treatment options include interferon α and vincristine which are reserved for life-threatening haemangiomas that are unresponsive to conventional therapy. This review mainly focuses on the current trends and evidence-based approach in the management of IH. |
format | Online Article Text |
id | pubmed-4134656 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-41346562014-08-18 Management of Infantile Hemangiomas: Current Trends Sethuraman, Gomathy Yenamandra, Vamsi K Gupta, Vishal J Cutan Aesthet Surg CME Article Infantile hemangiomas (IH) are common vascular tumours. IH have a characteristic natural course. They proliferate rapidly during the early infantile period followed by a period of gradual regression over several years. Most of the uncomplicated IH undergo spontaneous involution, with a small proportion of cases requiring intervention. These are children with IH in life-threatening locations, local complications like haemorrhage, ulceration and necrosis and functional or cosmetic disfigurements. Systemic corticosteroids have been the first line of treatment for many years. Recently, non-selective beta-blockers, such as oral propranalol and topical timolol, have emerged as promising and safer therapies. Other treatment options include interferon α and vincristine which are reserved for life-threatening haemangiomas that are unresponsive to conventional therapy. This review mainly focuses on the current trends and evidence-based approach in the management of IH. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4134656/ /pubmed/25136206 http://dx.doi.org/10.4103/0974-2077.138324 Text en Copyright: © Journal of Cutaneous and Aesthetic Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | CME Article Sethuraman, Gomathy Yenamandra, Vamsi K Gupta, Vishal Management of Infantile Hemangiomas: Current Trends |
title | Management of Infantile Hemangiomas: Current Trends |
title_full | Management of Infantile Hemangiomas: Current Trends |
title_fullStr | Management of Infantile Hemangiomas: Current Trends |
title_full_unstemmed | Management of Infantile Hemangiomas: Current Trends |
title_short | Management of Infantile Hemangiomas: Current Trends |
title_sort | management of infantile hemangiomas: current trends |
topic | CME Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134656/ https://www.ncbi.nlm.nih.gov/pubmed/25136206 http://dx.doi.org/10.4103/0974-2077.138324 |
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