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Subanesthetic Isoflurane Reduces Zymosan-Induced Inflammation in Murine Kupffer Cells by Inhibiting ROS-Activated p38 MAPK/NF-κB Signaling
Volatile anesthetic isoflurane (ISO) has immunomodulatory effects. The fungal component zymosan (ZY) induces inflammation through toll-like receptor 2 or dectin-1 signaling. We investigated the molecular actions of subanesthetic (0.7%) ISO against ZY-induced inflammatory activation in murine Kupffer...
Autores principales: | Wang, Hui, Wang, Lei, Li, Nan-lin, Li, Jun-tang, Yu, Feng, Zhao, Ya-li, Wang, Ling, Yi, Jun, Bian, Jie-fang, Chen, Jiang-hao, Yuan, Shi-fang, Wang, Ting, Lv, Yong-gang, Liu, Ning-ning, Zhu, Xiao-shan, Ling, Rui, Yun, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134815/ https://www.ncbi.nlm.nih.gov/pubmed/25147596 http://dx.doi.org/10.1155/2014/851692 |
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