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Association of chronic periodontitis with white blood cell and platelet count – A Case Control Study

Objectives:The objective of the study was to determine whether plasma levels of white blood corpuscles (WBCs) and platelets were altered in patients with chronic periodontitis compared to healthy controls. Study Design:A total of 120 subjects, 60 with chronic periodontitis and 60 with healthy period...

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Autores principales: Kumar, Balmuri P., Khaitan, Tanya, Ramaswamy, Pachigolla, Sreenivasulu, Pattipati, Uday, Ginjupally, Velugubantla, Ragha G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134847/
https://www.ncbi.nlm.nih.gov/pubmed/25136419
http://dx.doi.org/10.4317/jced.51292
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author Kumar, Balmuri P.
Khaitan, Tanya
Ramaswamy, Pachigolla
Sreenivasulu, Pattipati
Uday, Ginjupally
Velugubantla, Ragha G.
author_facet Kumar, Balmuri P.
Khaitan, Tanya
Ramaswamy, Pachigolla
Sreenivasulu, Pattipati
Uday, Ginjupally
Velugubantla, Ragha G.
author_sort Kumar, Balmuri P.
collection PubMed
description Objectives:The objective of the study was to determine whether plasma levels of white blood corpuscles (WBCs) and platelets were altered in patients with chronic periodontitis compared to healthy controls. Study Design:A total of 120 subjects, 60 with chronic periodontitis and 60 with healthy periodontium of age group 30-50 years were selected for the study. Oral hygiene status and pocket probing depth were measured. During clinical evaluation, venous blood samples were taken to analyze the WBC and platelet counts. Statistical analysis was utilized to compare differences across various groups. Results:The WBC count was higher in patients with chronic periodontitis when compared with controls whereas the platelet count was lower in the case group. Conclusions:Elevated WBC count plays a key role in chronic periodontitis and in turn a risk factor for cardiovascular diseases. However, there is no significant role of platelets in periodontal infection even though it has a major role in atherogenesis. Key words:Periodontitis, white blood cells, platelets, cardiovascular diseases.
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spelling pubmed-41348472014-08-18 Association of chronic periodontitis with white blood cell and platelet count – A Case Control Study Kumar, Balmuri P. Khaitan, Tanya Ramaswamy, Pachigolla Sreenivasulu, Pattipati Uday, Ginjupally Velugubantla, Ragha G. J Clin Exp Dent Research Objectives:The objective of the study was to determine whether plasma levels of white blood corpuscles (WBCs) and platelets were altered in patients with chronic periodontitis compared to healthy controls. Study Design:A total of 120 subjects, 60 with chronic periodontitis and 60 with healthy periodontium of age group 30-50 years were selected for the study. Oral hygiene status and pocket probing depth were measured. During clinical evaluation, venous blood samples were taken to analyze the WBC and platelet counts. Statistical analysis was utilized to compare differences across various groups. Results:The WBC count was higher in patients with chronic periodontitis when compared with controls whereas the platelet count was lower in the case group. Conclusions:Elevated WBC count plays a key role in chronic periodontitis and in turn a risk factor for cardiovascular diseases. However, there is no significant role of platelets in periodontal infection even though it has a major role in atherogenesis. Key words:Periodontitis, white blood cells, platelets, cardiovascular diseases. Medicina Oral S.L. 2014-07-01 /pmc/articles/PMC4134847/ /pubmed/25136419 http://dx.doi.org/10.4317/jced.51292 Text en Copyright: © 2014 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Kumar, Balmuri P.
Khaitan, Tanya
Ramaswamy, Pachigolla
Sreenivasulu, Pattipati
Uday, Ginjupally
Velugubantla, Ragha G.
Association of chronic periodontitis with white blood cell and platelet count – A Case Control Study
title Association of chronic periodontitis with white blood cell and platelet count – A Case Control Study
title_full Association of chronic periodontitis with white blood cell and platelet count – A Case Control Study
title_fullStr Association of chronic periodontitis with white blood cell and platelet count – A Case Control Study
title_full_unstemmed Association of chronic periodontitis with white blood cell and platelet count – A Case Control Study
title_short Association of chronic periodontitis with white blood cell and platelet count – A Case Control Study
title_sort association of chronic periodontitis with white blood cell and platelet count – a case control study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134847/
https://www.ncbi.nlm.nih.gov/pubmed/25136419
http://dx.doi.org/10.4317/jced.51292
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