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Association of chronic periodontitis with white blood cell and platelet count – A Case Control Study
Objectives:The objective of the study was to determine whether plasma levels of white blood corpuscles (WBCs) and platelets were altered in patients with chronic periodontitis compared to healthy controls. Study Design:A total of 120 subjects, 60 with chronic periodontitis and 60 with healthy period...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134847/ https://www.ncbi.nlm.nih.gov/pubmed/25136419 http://dx.doi.org/10.4317/jced.51292 |
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author | Kumar, Balmuri P. Khaitan, Tanya Ramaswamy, Pachigolla Sreenivasulu, Pattipati Uday, Ginjupally Velugubantla, Ragha G. |
author_facet | Kumar, Balmuri P. Khaitan, Tanya Ramaswamy, Pachigolla Sreenivasulu, Pattipati Uday, Ginjupally Velugubantla, Ragha G. |
author_sort | Kumar, Balmuri P. |
collection | PubMed |
description | Objectives:The objective of the study was to determine whether plasma levels of white blood corpuscles (WBCs) and platelets were altered in patients with chronic periodontitis compared to healthy controls. Study Design:A total of 120 subjects, 60 with chronic periodontitis and 60 with healthy periodontium of age group 30-50 years were selected for the study. Oral hygiene status and pocket probing depth were measured. During clinical evaluation, venous blood samples were taken to analyze the WBC and platelet counts. Statistical analysis was utilized to compare differences across various groups. Results:The WBC count was higher in patients with chronic periodontitis when compared with controls whereas the platelet count was lower in the case group. Conclusions:Elevated WBC count plays a key role in chronic periodontitis and in turn a risk factor for cardiovascular diseases. However, there is no significant role of platelets in periodontal infection even though it has a major role in atherogenesis. Key words:Periodontitis, white blood cells, platelets, cardiovascular diseases. |
format | Online Article Text |
id | pubmed-4134847 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-41348472014-08-18 Association of chronic periodontitis with white blood cell and platelet count – A Case Control Study Kumar, Balmuri P. Khaitan, Tanya Ramaswamy, Pachigolla Sreenivasulu, Pattipati Uday, Ginjupally Velugubantla, Ragha G. J Clin Exp Dent Research Objectives:The objective of the study was to determine whether plasma levels of white blood corpuscles (WBCs) and platelets were altered in patients with chronic periodontitis compared to healthy controls. Study Design:A total of 120 subjects, 60 with chronic periodontitis and 60 with healthy periodontium of age group 30-50 years were selected for the study. Oral hygiene status and pocket probing depth were measured. During clinical evaluation, venous blood samples were taken to analyze the WBC and platelet counts. Statistical analysis was utilized to compare differences across various groups. Results:The WBC count was higher in patients with chronic periodontitis when compared with controls whereas the platelet count was lower in the case group. Conclusions:Elevated WBC count plays a key role in chronic periodontitis and in turn a risk factor for cardiovascular diseases. However, there is no significant role of platelets in periodontal infection even though it has a major role in atherogenesis. Key words:Periodontitis, white blood cells, platelets, cardiovascular diseases. Medicina Oral S.L. 2014-07-01 /pmc/articles/PMC4134847/ /pubmed/25136419 http://dx.doi.org/10.4317/jced.51292 Text en Copyright: © 2014 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Kumar, Balmuri P. Khaitan, Tanya Ramaswamy, Pachigolla Sreenivasulu, Pattipati Uday, Ginjupally Velugubantla, Ragha G. Association of chronic periodontitis with white blood cell and platelet count – A Case Control Study |
title | Association of chronic periodontitis with white blood cell
and platelet count – A Case Control Study |
title_full | Association of chronic periodontitis with white blood cell
and platelet count – A Case Control Study |
title_fullStr | Association of chronic periodontitis with white blood cell
and platelet count – A Case Control Study |
title_full_unstemmed | Association of chronic periodontitis with white blood cell
and platelet count – A Case Control Study |
title_short | Association of chronic periodontitis with white blood cell
and platelet count – A Case Control Study |
title_sort | association of chronic periodontitis with white blood cell
and platelet count – a case control study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134847/ https://www.ncbi.nlm.nih.gov/pubmed/25136419 http://dx.doi.org/10.4317/jced.51292 |
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