Cargando…
MEN1-tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2
Recent studies suggest that physiological and tumorigenic proliferation of mammalian cells is controlled by multiple cyclin-dependent kinases (CDKs) largely in tissue-specific manners. We and others previously demonstrated that adult mice deficient for the D-cyclin-dependent kinase CDK4 (Cdk4(−/−) m...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135037/ https://www.ncbi.nlm.nih.gov/pubmed/24531709 http://dx.doi.org/10.1038/onc.2014.3 |