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Splenic Metastasis of Squamous Cell Carcinoma of the Uterine Cervix: A Case Report and Review of the Literature

Metastasis from various neoplasms to the spleen is very rare and most of the cases are found at autopsy. We report a patient presenting with uterine cervical cancer with splenic metastases. A 49-year-old woman presenting with genital bleeding was referred to our hospital and diagnosed with stage IIB...

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Autores principales: Taga, Shigeki, Sawada, Mari, Nagai, Aya, Yamamoto, Dan, Hayase, Ryoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135132/
https://www.ncbi.nlm.nih.gov/pubmed/25152820
http://dx.doi.org/10.1155/2014/798948
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author Taga, Shigeki
Sawada, Mari
Nagai, Aya
Yamamoto, Dan
Hayase, Ryoji
author_facet Taga, Shigeki
Sawada, Mari
Nagai, Aya
Yamamoto, Dan
Hayase, Ryoji
author_sort Taga, Shigeki
collection PubMed
description Metastasis from various neoplasms to the spleen is very rare and most of the cases are found at autopsy. We report a patient presenting with uterine cervical cancer with splenic metastases. A 49-year-old woman presenting with genital bleeding was referred to our hospital and diagnosed with stage IIB cervical cancer. She underwent concomitant chemoradiotherapy (CCRT) consisting of 50 Gy whole pelvis irradiation, high-dose-rate intracavitary brachytherapy 24 Gy/4 fractions and six weeks of paclitaxel and carboplatin administration. Ten months after the initial therapy, CT revealed recurrence at spleen. Although she received 5 courses of nedaplatin, enlargement of the tumor was noticed. She underwent a splenectomy and the result of histology was compatible with metastasis of cervical cancer.
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spelling pubmed-41351322014-08-24 Splenic Metastasis of Squamous Cell Carcinoma of the Uterine Cervix: A Case Report and Review of the Literature Taga, Shigeki Sawada, Mari Nagai, Aya Yamamoto, Dan Hayase, Ryoji Case Rep Obstet Gynecol Case Report Metastasis from various neoplasms to the spleen is very rare and most of the cases are found at autopsy. We report a patient presenting with uterine cervical cancer with splenic metastases. A 49-year-old woman presenting with genital bleeding was referred to our hospital and diagnosed with stage IIB cervical cancer. She underwent concomitant chemoradiotherapy (CCRT) consisting of 50 Gy whole pelvis irradiation, high-dose-rate intracavitary brachytherapy 24 Gy/4 fractions and six weeks of paclitaxel and carboplatin administration. Ten months after the initial therapy, CT revealed recurrence at spleen. Although she received 5 courses of nedaplatin, enlargement of the tumor was noticed. She underwent a splenectomy and the result of histology was compatible with metastasis of cervical cancer. Hindawi Publishing Corporation 2014 2014-07-24 /pmc/articles/PMC4135132/ /pubmed/25152820 http://dx.doi.org/10.1155/2014/798948 Text en Copyright © 2014 Shigeki Taga et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Taga, Shigeki
Sawada, Mari
Nagai, Aya
Yamamoto, Dan
Hayase, Ryoji
Splenic Metastasis of Squamous Cell Carcinoma of the Uterine Cervix: A Case Report and Review of the Literature
title Splenic Metastasis of Squamous Cell Carcinoma of the Uterine Cervix: A Case Report and Review of the Literature
title_full Splenic Metastasis of Squamous Cell Carcinoma of the Uterine Cervix: A Case Report and Review of the Literature
title_fullStr Splenic Metastasis of Squamous Cell Carcinoma of the Uterine Cervix: A Case Report and Review of the Literature
title_full_unstemmed Splenic Metastasis of Squamous Cell Carcinoma of the Uterine Cervix: A Case Report and Review of the Literature
title_short Splenic Metastasis of Squamous Cell Carcinoma of the Uterine Cervix: A Case Report and Review of the Literature
title_sort splenic metastasis of squamous cell carcinoma of the uterine cervix: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135132/
https://www.ncbi.nlm.nih.gov/pubmed/25152820
http://dx.doi.org/10.1155/2014/798948
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