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Synthesis, Characterization and In Vitro Anticancer Activity of C-5 Curcumin Analogues with Potential to Inhibit TNF-α-Induced NF-κB Activation

In a search of new compounds active against cancer, synthesis of a series of C-5 curcumin analogues was carried out. The new compounds demonstrated good cytotoxicity against chronic myeloid leukemia (KBM5) and colon cancer (HCT116) cell lines. Further, these compounds were found to have better poten...

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Detalles Bibliográficos
Autores principales: Anthwal, Amit, Thakur, Bandana K., Rawat, M. S. M., Rawat, D. S., Tyagi, Amit K., Aggarwal, Bharat B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135142/
https://www.ncbi.nlm.nih.gov/pubmed/25157362
http://dx.doi.org/10.1155/2014/524161

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