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Synthesis, Characterization and In Vitro Anticancer Activity of C-5 Curcumin Analogues with Potential to Inhibit TNF-α-Induced NF-κB Activation
In a search of new compounds active against cancer, synthesis of a series of C-5 curcumin analogues was carried out. The new compounds demonstrated good cytotoxicity against chronic myeloid leukemia (KBM5) and colon cancer (HCT116) cell lines. Further, these compounds were found to have better poten...
Autores principales: | Anthwal, Amit, Thakur, Bandana K., Rawat, M. S. M., Rawat, D. S., Tyagi, Amit K., Aggarwal, Bharat B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135142/ https://www.ncbi.nlm.nih.gov/pubmed/25157362 http://dx.doi.org/10.1155/2014/524161 |
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