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A Pilot Study on Pain and the Upregulation of Myoglobin through Low-frequency and High-amplitude Electrical Stimulation-induced Muscle Contraction

[Purpose] It is well known that, in both in vivo and in vitro tests, muscle fatigue is produced by severe exercise, electrical stimulation, and so on. However, it is not clear whether or not low-frequency and high-amplitude modulation specifically affects serum myoglobin or urine myoglobin. The purp...

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Autores principales: Lee, Lim-Kyu, Kim, Ju-Hyun, Kim, Mee-Young, Lee, Jeong-Uk, Yang, Seung-Min, Jeon, Hye-Joo, Lee, Won-Deok, Noh, Ji-Woong, Kwak, Taek-Yong, Jang, Sung-Ho, Lee, Tae-Hyun, Kim, Ju-Young, Kim, Junghwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society of Physical Therapy Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135220/
https://www.ncbi.nlm.nih.gov/pubmed/25140079
http://dx.doi.org/10.1589/jpts.26.985
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author Lee, Lim-Kyu
Kim, Ju-Hyun
Kim, Mee-Young
Lee, Jeong-Uk
Yang, Seung-Min
Jeon, Hye-Joo
Lee, Won-Deok
Noh, Ji-Woong
Kwak, Taek-Yong
Jang, Sung-Ho
Lee, Tae-Hyun
Kim, Ju-Young
Kim, Junghwan
author_facet Lee, Lim-Kyu
Kim, Ju-Hyun
Kim, Mee-Young
Lee, Jeong-Uk
Yang, Seung-Min
Jeon, Hye-Joo
Lee, Won-Deok
Noh, Ji-Woong
Kwak, Taek-Yong
Jang, Sung-Ho
Lee, Tae-Hyun
Kim, Ju-Young
Kim, Junghwan
author_sort Lee, Lim-Kyu
collection PubMed
description [Purpose] It is well known that, in both in vivo and in vitro tests, muscle fatigue is produced by severe exercise, electrical stimulation, and so on. However, it is not clear whether or not low-frequency and high-amplitude modulation specifically affects serum myoglobin or urine myoglobin. The purpose of the present study was to determine the effect of low-frequency and high-amplitude modulation on serum myoglobin and urine myoglobin. [Methods] The study used whole blood samples and urine produced over 24 hours from the thirteen healthy subjects. [Results] There was a significant increase in serum myoglobin following electrical stimulation at a frequency of 10 Hz compared with the control group. Furthermore, within 24 hours, urine myoglobin also showed a significant increase for the test volunteers subjected to electrical stimulation at the 10 Hz frequency compared with the control group. However, there were no significant differences in the concentrations of hematologic results in subjects treated with electrical stimulation. [Conclusion] These results suggest that increased myoglobin related to muscle fatigue from electrical stimulation, particularly with a current of 10 Hz combined with a high-amplitude, may be partially related to increased muscle damage.
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spelling pubmed-41352202014-08-19 A Pilot Study on Pain and the Upregulation of Myoglobin through Low-frequency and High-amplitude Electrical Stimulation-induced Muscle Contraction Lee, Lim-Kyu Kim, Ju-Hyun Kim, Mee-Young Lee, Jeong-Uk Yang, Seung-Min Jeon, Hye-Joo Lee, Won-Deok Noh, Ji-Woong Kwak, Taek-Yong Jang, Sung-Ho Lee, Tae-Hyun Kim, Ju-Young Kim, Junghwan J Phys Ther Sci Original Article [Purpose] It is well known that, in both in vivo and in vitro tests, muscle fatigue is produced by severe exercise, electrical stimulation, and so on. However, it is not clear whether or not low-frequency and high-amplitude modulation specifically affects serum myoglobin or urine myoglobin. The purpose of the present study was to determine the effect of low-frequency and high-amplitude modulation on serum myoglobin and urine myoglobin. [Methods] The study used whole blood samples and urine produced over 24 hours from the thirteen healthy subjects. [Results] There was a significant increase in serum myoglobin following electrical stimulation at a frequency of 10 Hz compared with the control group. Furthermore, within 24 hours, urine myoglobin also showed a significant increase for the test volunteers subjected to electrical stimulation at the 10 Hz frequency compared with the control group. However, there were no significant differences in the concentrations of hematologic results in subjects treated with electrical stimulation. [Conclusion] These results suggest that increased myoglobin related to muscle fatigue from electrical stimulation, particularly with a current of 10 Hz combined with a high-amplitude, may be partially related to increased muscle damage. The Society of Physical Therapy Science 2014-07-30 2014-07 /pmc/articles/PMC4135220/ /pubmed/25140079 http://dx.doi.org/10.1589/jpts.26.985 Text en 2014©by the Society of Physical Therapy Science http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Original Article
Lee, Lim-Kyu
Kim, Ju-Hyun
Kim, Mee-Young
Lee, Jeong-Uk
Yang, Seung-Min
Jeon, Hye-Joo
Lee, Won-Deok
Noh, Ji-Woong
Kwak, Taek-Yong
Jang, Sung-Ho
Lee, Tae-Hyun
Kim, Ju-Young
Kim, Junghwan
A Pilot Study on Pain and the Upregulation of Myoglobin through Low-frequency and High-amplitude Electrical Stimulation-induced Muscle Contraction
title A Pilot Study on Pain and the Upregulation of Myoglobin through Low-frequency and High-amplitude Electrical Stimulation-induced Muscle Contraction
title_full A Pilot Study on Pain and the Upregulation of Myoglobin through Low-frequency and High-amplitude Electrical Stimulation-induced Muscle Contraction
title_fullStr A Pilot Study on Pain and the Upregulation of Myoglobin through Low-frequency and High-amplitude Electrical Stimulation-induced Muscle Contraction
title_full_unstemmed A Pilot Study on Pain and the Upregulation of Myoglobin through Low-frequency and High-amplitude Electrical Stimulation-induced Muscle Contraction
title_short A Pilot Study on Pain and the Upregulation of Myoglobin through Low-frequency and High-amplitude Electrical Stimulation-induced Muscle Contraction
title_sort pilot study on pain and the upregulation of myoglobin through low-frequency and high-amplitude electrical stimulation-induced muscle contraction
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135220/
https://www.ncbi.nlm.nih.gov/pubmed/25140079
http://dx.doi.org/10.1589/jpts.26.985
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