Maternal Pre-Gravid Obesity Changes Gene Expression Profiles Towards Greater Inflammation and Reduced Insulin Sensitivity in Umbilical Cord

BACKGROUND: Maternal obesity is associated with unfavorable outcomes, which may be reflected in the as yet undiscovered gene expression profiles of the umbilical cord (UC). METHODS: UCs from 12 lean (pre-gravid BMI < 24.9) and 10 overweight/obese (OW/OB, pre-gravid BMI ≥25) women without gestatio...

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Detalles Bibliográficos
Autores principales: Thakali, Keshari M., Saben, Jessica, Faske, Jennifer B., Lindsey, Forrest, Gomez-Acevedo, Horacio, Lowery, Curtis L., Badger, Thomas M., Andres, Aline, Shankar, Kartik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135718/
https://www.ncbi.nlm.nih.gov/pubmed/24819376
http://dx.doi.org/10.1038/pr.2014.72

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