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Putative Kappa Opioid Heteromers As Targets for Developing Analgesics Free of Adverse Effects
[Image: see text] It is now generally recognized that upon activation by an agonist, β-arrestin associates with G protein-coupled receptors and acts as a scaffold in creating a diverse signaling network that could lead to adverse effects. As an approach to reducing side effects associated with κ opi...
Autores principales: | Le Naour, Morgan, Lunzer, Mary M., Powers, Michael D., Kalyuzhny, Alexander E., Benneyworth, Michael A., Thomas, Mark J., Portoghese, Philip S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136663/ https://www.ncbi.nlm.nih.gov/pubmed/24978316 http://dx.doi.org/10.1021/jm500159d |
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