Cargando…
Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress: Miniperspective
[Image: see text] Protein structure underlies essential biological processes and provides a blueprint for molecular mimicry that drives drug discovery. Although small molecules represent the lion’s share of agents that target proteins for therapeutic benefit, there remains no substitute for the natu...
Autores principales: | Walensky, Loren D., Bird, Gregory H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136684/ https://www.ncbi.nlm.nih.gov/pubmed/24601557 http://dx.doi.org/10.1021/jm4011675 |
Ejemplares similares
-
Biophysical Determinants for Cellular Uptake of Hydrocarbon-Stapled Peptide Helices
por: Bird, Gregory H., et al.
Publicado: (2016) -
Stapled HIV-1 Peptides Recapitulate Antigenic Structures and Engage Broadly Neutralizing Antibodies
por: Bird, Gregory H., et al.
Publicado: (2014) -
Hydrocarbon Stapled Antimicrobial Peptides
por: Migoń, Dorian, et al.
Publicado: (2018) -
Mechanistic Validation of a Clinical Lead Stapled Peptide that Reactivates p53 by Dual HDM2 and HDMX Targeting
por: Wachter, Franziska, et al.
Publicado: (2016) -
Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function
por: Hawley, Katrina M., et al.
Publicado: (2022)