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N-Methylimidazole Promotes the Reaction of Homophthalic Anhydride with Imines

[Image: see text] The addition of N-methylimidazole (NMI) to the reaction of homophthalic anhydride with imines such as pyridine-3-carboxaldehyde-N-trifluoroethylimine (9) reduces the amount of elimination byproduct and improves the yield of the formal cycloadduct, tetrahydroisoquinolonic carboxylat...

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Detalles Bibliográficos
Autores principales: Liu, Jian, Wang, Zheng, Levin, Aaron, Emge, Thomas J., Rablen, Paul R., Floyd, David M., Knapp, Spencer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136697/
https://www.ncbi.nlm.nih.gov/pubmed/25036978
http://dx.doi.org/10.1021/jo501316m