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Modular Isotopomer Synthesis of γ-Hydroxybutyric Acid for a Quantitative Analysis of Metabolic Fates
[Image: see text] Herein we report a study combining metabolomics and mass isotopomer analysis used for investigation of the biochemical fate of γ-hydroxybutyric acid (GHB). Using various (13)C incorporation labeling patterns into GHB, we have discovered that GHB is catabolized by previously unknown...
Autores principales: | Sadhukhan, Sushabhan, Zhang, Guo-Fang, Tochtrop, Gregory P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136706/ https://www.ncbi.nlm.nih.gov/pubmed/24933109 http://dx.doi.org/10.1021/cb500380b |
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