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The Ca(2+) Sensor Protein Swiprosin-1/EFhd2 Is Present in Neurites and Involved in Kinesin-Mediated Transport in Neurons
Swiprosin-1/EFhd2 (EFhd2) is a cytoskeletal Ca(2+) sensor protein strongly expressed in the brain. It has been shown to interact with mutant tau, which can promote neurodegeneration, but nothing is known about the physiological function of EFhd2 in the nervous system. To elucidate this question, we...
Autores principales: | Purohit, Pavitra, Perez-Branguli, Francesc, Prots, Iryna, Borger, Eva, Gunn-Moore, Frank, Welzel, Oliver, Loy, Kristina, Wenzel, Eva Maria, Grömer, Teja W., Brachs, Sebastian, Holzer, Max, Buslei, Rolf, Fritsch, Kristin, Regensburger, Martin, Böhm, Konrad J., Winner, Beate, Mielenz, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136728/ https://www.ncbi.nlm.nih.gov/pubmed/25133820 http://dx.doi.org/10.1371/journal.pone.0103976 |
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